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. 2019 Aug 1;14(8):e0220404. doi: 10.1371/journal.pone.0220404

Table 1. Baseline hemodynamic and physical parameters.

WT TLR4-/- WT + MTS 510
n = 38 n = 37 n = 15
baseline before preparation for CA/CPR
body weight [g] 20,67 [± 2,0] 22,08 [± 3,1] 20,44 [± 1,4]
heart rate [1/min] 244 [± 32] 233 [± 23] 241 [± 31]
MAP [mm Hg] 101 [± 11] 90 [± 11] 94 [± 8]
body temperature [°C] 36,0 [± 0,1] 36,0 [± 0,1] 36,0 [± 0,1]
parameter of CA/CPR
ROSC time [s] 84 [± 25] 77 [± 20] 65 [± 22]
ROSC rate 100% 100% 100%
Adrenalin (μg) 15,0 [10 – 15] 12,5 [10 – 15] 12,5 [10 – 15]
weaning (min) 140 [± 12] 137 [± 10] 136 [± 8]
1 hour after CA/CPR
heart rate [1/min] 429 [± 37] 457 [± 26] 440 [± 42]
MAP [mm Hg] 67 [± 8] 63 [± 12] 71 [± 10]
body temperature [°C] 36,4 [± 0,2] 36,0 [± 0,3] 36,2 [± 0,1]
2 hours after CA/CPR
heart rate [1/min] 277 [± 27] 301 [± 33] 287 [± 27]
MAP [mm Hg] 60 [± 10] 65 [± 15] 64 [± 12]
body temperature [°C] 36,0 [± 0,2] 36,0 [± 0,1] 36,1 [± 0,2]
observation period after CA/CPR
body temperature
4 h post CA/CPR [°C] 35,4 [± 0,8] 35,0 [± 0,9] 35,7 [± 0,5]
8 h post CA/CPR [°C] 35,2 [± 1,0] 34,8 [± 1,3] 35,1 [± 1,2]
12 h post CA/CPR [°C] 35,8 [± 0,9] 35,2 [± 0,8] 35,2 [± 0,9]
24 h post CA/CPR [°C] 35,0 [± 1,2] 35,4 [± 1,1] 35,1 [± 1,4]
adverse events
seizures [n] 4 5 2
paresis of hind limbs
irreversible [n] 5 4 1
reversible [n] 1 2 1