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. 2019 Aug 1;14(8):e0220404. doi: 10.1371/journal.pone.0220404

Table 4. Water maze test.

WT WT+MTS 510 TLR4-/-
n = 38 n = 15 n = 37
training phase before CA/CPR—first position of escape platform
first attempt prior CA/CPR day -5 time [s] 18 [9 – 35] 13 [7 – 36]
last attempt prior CA/CPR day -1 time [s] 4 [2 – 18] 6 [3 – 17]
after CA/CPR—first position of escape platform (remembrance of position)
first attempt after CA/CPR day X time [s] 8 [3 – 18] 7 [4 – 26] 15 [7 – 28]
last attempt after CA/CPR day X+2 time [s] 6 [3 – 14] 3 [2 – 4] 8 [5 – 16]
after CA/CPR—alternative position of escape platform (new spatial learning)
first attempt new position day 10 time [s] 12 [6 – 28] 9 [6 – 23] 10 [3 – 22]
end of training phase day 15 time [s] 8 [1 – 12] 3 [3 – 4] 9 [3 – 22]
participation in the Water Maze Test after CA/CPR
paticipants after CA/CPR n [%] 15 [39,5] 5 [33,3] 19 [51,4]
earliest day of participation after CA/CPR (day X) day 5 [4 – 6] 4 [3 – 5] 6 [4 – 7]
Requirements for participation in the Water Maze Test after CA/CPR
to get full marks for the NeuroScore 12 of 12 points
to complete one of three attempts in RotaRod-Test without falling from the rod [300 sec]
show recovery of bodyweight
no signs of disturbance