Table 1.
Expression analysis in WT (n = 6) and GSK (n = 6) male mouse brain
| WT, cortex | GSK, cortex | WT, striatum | GSK, striatum | |
|---|---|---|---|---|
| Human GSK-3β | 0.00 ± 0.00 | 3.01 ± 0.21 ** | 0.00 ± 0.00 | 1.39 ± 0.17** |
| Murine GSK-3β | 1.17 ± 0.10 | 1.68 ± 0.11* | 1.60 ± 0.24 | 1.61 ± 0.70 |
| Murine GSK-3α | 2.21 ± 0.15 | 1.90 ± 0.11 | 1.73 ± 0.07 | 1.23 ± 0.14* |
| Murine Akt-1 | 3.35 ± 0.70 | 5.37 ± 1.47 | 2.70 ± 0.14 | 5.61 ± 0.46** |
| Murine PPP2R3A | 1.51 ± 0.16 | 1.42 ± 0.11 | 2.00 ± 0.17 | 1.26 ± 0.08* |
| Murine PDK1 | 1.56 ± 0.04 | 1.43 ± 0.13 | 2.08 ± 0.20 | 1.96 ± 0.28 |
| Murine DARP32 | 2.56 ± 0.35 | 2.30 ± 0.41 | 25.26 ± 3.44 | 27.96 ± 1.48 |
Values are shown as means ± SEM.
*p < 0.01 and
**p < 0.001 (t test; different between WT and GSK mice for the same region).