Table 1.
Characteristics of flash responses of rods with and without arrestin splice variants
|
|
Dark current (pA) |
Time-to-peak (ms) |
Elementary amplitude (pA) |
τrec (s) |
Integration time (ms) |
Ioa (photons/μm2) |
|---|---|---|---|---|---|---|
| WT | 12.2 ± 0.6 (31) | 133 ± 8 (23) | 0.43 ± 0.05 (20) | 0.23 ± 0.02 (23) | 317 ± 28 (23) | 77.9 ± 5.9 (21) |
| m44Arr—/— | 11.3 ± 0.9 (22) | 144 ± 15 (20) | 0.48 ± 0.09 (16) | 0.24 ± 0.02 (20) | 315 ± 39 (20) | 69.2 ± 6.3 (19) |
| p48Arr—/— | 11.4 ± 0.7 (23) | 130 ± 12 (20) | 0.44 ± 0.05 (18) | 0.30 ± 0.09 (19) | 407 ± 56 (20) | 77.8 ± 5.4 (21) |
| Arr—/— |
9.6 ± 1.1 (9) |
220 ± 56 (6) |
ND |
26.0 ± 9.1 (6) |
ND |
ND |
ND, Not determined.
a
Flash strength that elicited a half-maximal response.