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. 2006 Jan 18;26(3):971–980. doi: 10.1523/JNEUROSCI.4423-05.2006

Figure 3.

Figure 3.

Effects of the antagonist selective for mGluR1 (CPCCOet; A) or mGluR5 (MPEP; B) on basal and DHPG-induced JNK phosphorylation in cultured rat striatal neurons. CPCCOet (1 or 5μm) or MPEP (1 and 5μm) was incubated 30 min before and during a 10 min treatment with DHPG(100μm). Note that MPEP blocked, whereas CPCCOet had no effect on, the DHPG-induced JNK phosphorylation. Representative immunoblots are shown to the left of the quantified data of pJNK1. Values are expressed in terms of mean ± SEM (n = 4–6). *p < 0.05 versus basal levels. +p < 0.05 versus DHPG alone.