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. Author manuscript; available in PMC: 2020 Feb 27.
Published in final edited form as: Cell Syst. 2019 Feb 20;8(2):97–108.e16. doi: 10.1016/j.cels.2019.01.003

Figure 3: Synergistic efficacy and/or potency of drug combinations in BRAF-mutant melanoma.

Figure 3:

A) 8 BRAF-mutant melanoma cell lines were treated with all possible pairwise combinations of 4 RAF and 4 MEK inhibitors (Table S2) for a total of 128 unique combinations. Waterfall plots of βobs for each cell line with all combinations which converged in fitting. Drug combinations noted by letter in the legend to right. (Also see Figure S5).