Table 1.
Parameter | Symbol | ValueI | ValueII | Units | Reference |
---|---|---|---|---|---|
Surface area of PSD | APSD | 0.1257a | μm2 | Sorra and Harris, 2000 | |
Surface area of ESM | AESM | 1.257a | μm2 | Sorra and Harris, 2000 | |
Concentration of binding sites | L | 159.15a | μm−2 | This paper | |
Number of intracellular receptors | S | 500 | 100 | This paper | |
Exocytic rate per intracellular receptor | κ | 0.0005556 | 0.001667 | s−1 | Passafaro et al., 2001 |
Rate of exocytosis | σ | 0.2778 | 0.1667 | s−1 | Passafaro et al., 2001 |
Rate of endocytosis | k | 0.01667 | 0.01667 | s−1 | Ehlers, 2000 |
PSD–ESM hopping rate | h | 0.001257 | 0.001257 | μm2 s−1 | This paper |
ESM–dendrite hopping rate | Ω | 0.001257 | 0.001257 | μm2 s−1 | This paper |
Background receptor concentration | R̄ | 10 | 0 | μm−2 | Cottrell et al., 2000 |
Binding rate to scaffolding protein | α | 10−6 | 10−4 | μm2 s−1 | This paper |
Release rate from scaffolding protein | β | 10−5 | 10−5 | s−1 | This paper |
aThe nontrafficking parameters do not have particular type I and II values.