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Fornix lesions prevent induction of hippocampal Arc mRNA after water maze training. A, Sham Arc mRNA levels were significantly higher than lesion or home-cage control groups. Arc mRNA levels did not differ between lesion and home-cage control groups. B, Pseudocolored autoradiographs demonstrate hippocampal Arc mRNA expression in sham and lesion animals. ***p = 0.001, statistically significant. Error bars indicate SEM.
