Figure 5.

Fornix lesions do not prevent induction of Arc expression in response to MPP potentiation. A, HFS of the MPP resulted in similar potentiation in sham and lesion animals. Representative pre- and post-HFS EPSPs from sham and lesion animals demonstrate potentiation of responses (inset). B, Arc mRNA levels did not differ between sham and lesion groups. GCL, Granular cell layer; ML, molecular layer. C, Pseudocolored autoradiographs demonstrate Arc mRNA expression in the stimulated ipsilateral but not the unstimulated contralateral hippocampus of sham and lesion animals.