Figure 4.

Effects of COMT Val108/158Met polymorphism on memory-related brain activity. Compared with Met homozygous subjects, Val homozygous subjects show increased memory-related activations of the right prefrontal cortex (A) and of the cuneus, extending into the primary visual cortex (B). Activations above a threshold of T > 2.72 (p < 0.005, uncorrected; extent threshold, k = 10 voxels) are displayed. Bar plots display the same information as in Figure 3. [x, y, z], Voxel coordinates in MNI reference space.