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. 2006 Feb 1;26(5):1579–1587. doi: 10.1523/JNEUROSCI.4132-05.2006

Figure 2.

Figure 2.

Cocaine alters ABPs that regulate actin depolymerization. For treatment regimens, see Figure 1a. a, Effect of cocaine on ABPs in the nucleus accumbens. b, Effect of cocaine on LIMK in the prefrontal cortex. Data are shown as mean ± SEM, and the number of determinations is shown in each bar. Data were evaluated using a two-way ANOVA (acute × chronic): p-cofilin, acute, F(1,17) = 6.87, p = 0.018; chronic, F(1,17) = 8.81, p = 0.009; LIMK, chronic, F(1,26) = 6.21, p = 0.019; prefrontal cortex, chronic, F(1,27) = 4.70, p = 0.039. *p < 0.05 comparing repeated saline with repeated cocaine. +p < 0.05 comparing acute saline with acute cocaine.