Skip to main content
. 2019 Aug 1;10(4):807–817. doi: 10.14336/AD.2018.0728

Figure 5. Necrostatin-1 treatment inhibited ischemia-induced expression of RIPK3/MLKL and formation of IL-1β in rat brains after MCAO.

Figure 5.

Expression levels of RIPK3, MLKL, p-MLKL and IL-1β (A) in the ipsilateral (IPSI) and contralateral (CON) striatum at 24 h after MCAO. Statistical analysis showed that Nec-1 treatment significantly suppressed RIPK3 (B), MLKL (C), p-MLKL (D) and mature IL-1β (E) expression levels in the ipsilateral striatum of MCAO rats compared with iNec-1 treatment (CON), n=4, *p<0.05.