Skip to main content
. 2019 Jul 25;4(14):e124497. doi: 10.1172/jci.insight.124497

Figure 5. Levels of major endogenous itch mediators in the skin and plasma of oxazolone and urushiol ACD models, measured by ELISA.

Figure 5

(A) Average protein concentrations of substance P, TSLP, 5-HT, ET-1, LTB4, and histamine in neck skin extracts of oxazolone-induced and urushiol-induced ACD mice compared with vehicle control mice. (B) The concentrations of itch mediators in the plasma of the same group of mice. Data in bar graphs are expressed as mean ± SEM. n = 5–7 mice/group. *P < 0.05, **P < 0.01, and ##P < 0.01. NS, no significance. One-way ANOVA followed by Tukey’s post hoc test was used for statistical analysis.