Table 1:
Sample characteristics of discovery and replication cohorts
Phase | Sample | N cohorts | N Suicide attempters (%) | N Non-attempters (%) | N Female | N Female |
---|---|---|---|---|---|---|
Suicide attempters (%) | Non-attempters (%) | |||||
Discovery | PGC Major depressive disorder | 16 | 1622 (16%) | 8786 (84%) | 1155 (71%) | 5808 (66%) |
PGC Bipolar disorder | 21 | 3264 (37%) | 5500 (63%) | 2097 (66%) | 2971 (56%) | |
PGC Schizophrenia | 9 | 1683 (36%) | 2946 (64%) | 660 (39%) | 924 (31%) | |
Total | 46 | 6569 (28%) | 17232 (72%) | 3912 (60%) | 9703 (56%) | |
Replication | UK Biobank (mood disorders*) | 1 | 2149 (6%) | 35912 (94%) | 1521 (71%) | 24039 (67%) |
iPSYCH (mood disorders*) | 1 | 4943 (24%) | 15849 (76%) | 3694 (75%) | 10276 (65%) |
PGC, Psychiatric Genomics Consortium
All samples in the UK Biobank and iPSYCH replication cohorts had depression or bipolar disorder.