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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Clin Gastroenterol Hepatol. 2019 Feb 1;17(11):2227–2235.e1. doi: 10.1016/j.cgh.2019.01.041

Table 1.

Characteristics of genetic variants associated with 25(OH)D concentration in published genome-wide association studies (ref.16)

SNP Chr Gene Effect/Reference Allele Effect Allele Frequency β estimate* s.e. P value
rs10741657 11 CYP2R1 A/G 0.40 0.031 0.0022 2.1 × 1−46
rs10745742 12 AMDHD1 T/C 0.40 0.017 0.0022 1.9 × 10−14
rsl2785878 11 DHCR7 T/G 0.75 0.036 0.0022 3.8 × 10−62
rs17216707 20 CYP24A1 T/C 0.79 0.026 0.0027 8.1 × 10−23
rs3755967 4 GC C/T 0.62 0.089 0.0023 4.7 × 10−343
rs8018720 14 SEC23A G/C 0.18 0.017 0.0029 4.7 × 10−9
*

25(OH)D level was reported SD increases in nmol/L in natural-log scale per copy of the effect alleles.