Table 3.
Characteristics of genetic variants associated with Barrett’s esophagus and esophageal adenocarcinoma
| SNP | Chr | Gene | Effect/Reference Allele | BE | EAC | ||
|---|---|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | ||||
| rs10741657 | 11 | CYP2R1 | A/G | 1.01 (0.97–1.06) | 0.577 | 0.98 (0.93–1.04) | 0.465 |
| rs10745742 | 12 | AMDHD1 | T/C | 0.97 (0.92–1.01) | 0.122 | 1.01 (0.95–1.06) | 0.811 |
| rsl2785878 | 11 | DHCR7 | T/G | 1.07 (1.02–1.13) | 0.008 | 0.99 (0.93–1.05) | 0.785 |
| rs17216707 | 20 | CYP24A1 | T/C | 0.98 (0.92–1.04) | 0.495 | 1.00 (0.93–1.08) | 0.920 |
| rs3755967 | 4 | GC | C/T | 1.00 (0.96–1.05) | 0.844 | 0.96 (0.91–1.02) | 0.213 |
| rs8018720 | 14 | SEC23A | G/C | 1.01 (0.95–1.06) | 0.841 | 0.99 (0.92–1.06) | 0.778 |