Table 3. Independent predictors of 12-month major adverse cardiovascular events.
| Variable | Univariate analysis | Multivariate Cox regression analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| Multiple overlapping vs. single stenting | 5.079 (2.311–11.163) | <0.001 | 3.879 (1.779 – 8.459) | 0.001 |
| Previous CHF | 9.990 (2.014–49.556) | 0.026 | 8.071 (1.307–49.855) | 0.003 |
| Multi-vessel disease | 6.800 (2.029–22.795) | <0.001 | 5.248 (1.557–17.689) | 0.007 |
| Age ≥75 years | 3.247 (1.447–7.285) | 0.003 | 2.489 (1.097–5.648) | 0.029 |
| Diabetes mellitus | 2.021 (0.927–4.410) | 0.072 | 1.570 (0.717–3.436) | 0.259 |
| Previous MI | 3.598 (0.800–16.178) | 0.075 | 1.398 (0.223–8.779) | 0.721 |
| Chronic total occlusion | 2.546 (0.739–8.778) | 0.125 | - | - |
| Statin | 1.921 (0.717–5.142) | 0.187 | - | - |
| TFI vs. TRI | 1.606 (0.737–3.501) | 0.230 | - | - |
| Potent P2Y12 inhibitors | 1.646 (0.556–4.873) | 0.364 | - | - |
| Diagnosed with MI | 0.715 (0.327–1.562) | 0.398 | - | - |
| Hypertension | 0.748 (0.343–1.630) | 0.463 | - | - |
| LVEF <50% | 1.416 (0.547–3.667) | 0.472 | - | - |
| Current smoker | 1.432 (0.591–3.046) | 0.481 | - | - |
| Dyslipidemia | 0.730 (0.302–1.766) | 0.484 | - | - |
| Beta-blocker | 1.222 (0.549–2.722) | 0.623 | - | - |
| Male sex | 1.203 (0.530–2.729) | 0.658 | - | - |
| Previous CVA | 1.306 (0.301–5.662) | 0.720 | - | - |
| Calcium channel blocker | 0.865 (0.322–2.323) | 0.774 | - | - |
| ACEi or ARB | 0.949 (0.431–2.088) | 0.896 | - | - |
ACEi = angiotensin converting enzyme inhibitor; ARB = angiotensin II receptor blocker; CHF = congestive heart failure; CI = confidence interval; CVA = cerebrovascular accident; HR = hazard ratio; LVEF = left ventricular ejection fraction; MI = myocardial infarction; TFI = trans-femoral intervention; TRI = trans-radial intervention.