Figure 7.

The rescue effects of miR‐219a‐5p and BIRC3 on breast cancer cells proliferation, migration and invasion. A, CCK8 assay to evaluate the rescue effect of miR‐219a‐5p inhibitor and BIRC3 on MDA‐MB‐468 cells proliferation after HCP5 knockdown and the rescue effect of miR‐219a‐5p mimics and BIRC3 siRNA on MDA‐MB‐231 cells proliferation after HCP5 overexpression. B, Transwell assay to detect the rescue effect of miR‐219a‐5p and BIRC3 on MDA‐MB‐468 or MDA‐MB‐231 cells migration and invasion after HCP5 knockdown or overexpression. ^* P < 0.05 and ^** P < 0.01, compared with control group. Two‐sided Student's t test; n = 3