Table 1.
Characteristics of 4249 patients with thin melanoma according to the 8th edition of the American Joint Committee on Cancer Staging Manual
| Characteristic | No. | % |
|---|---|---|
| Sex | ||
| Male | 1897 | 44.6 |
| Female | 2352 | 55.4 |
| Age of diagnosis | ||
| Median | 57.8 | |
| p75‐p25 | 40‐66 | |
| ≤40 y old | 1120 | 26.5 |
| 41‐65 y old | 2034 | 48.1 |
| >65 y old | 1071 | 25.3 |
| Anatomic location (missing = 133; 3.1%) | ||
| Head and neck | 494 | 12 |
| Trunk | 1746 | 42.4 |
| Upper extremities | 1261 | 30.6 |
| Lower extremities | 615 | 14.9 |
| Breslow thickness | ||
| Median | 0.6 | |
| p75‐p25 | 0.4‐0.8 | |
| <0.8 | 3018 | 71 |
| 0.8‐1.0 | 1231 | 29 |
| Ulceration (missing = 495; 11.6%) | ||
| Absent | 3613 | 96.2 |
| Present | 141 | 3.8 |
| Mitotic rate (missing = 1752; 41.2%) | ||
| 0 mitoses/mm2 | 1674 | 67 |
| 1 mitosis/mm2 | 514 | 20.6 |
| 2 mitoses/mm2 | 176 | 7 |
| >2 mitoses/mm2 | 133 | 5.3 |
| Histologic subtypes (missing = 64; 1.5%) | ||
| LMM | 346 | 8.3 |
| SSM | 3487 | 83.3 |
| NM | 89 | 2.1 |
| ALM | 94 | 2.2 |
| Other | 169 | 4 |
| Clark level (missing = 973; 22.9%) | ||
| II‐III | 2838 | 86.6 |
| IV‐V | 438 | 13.4 |
| Lymphovascular invasion (missing = 1887; 44.4%) | ||
| Absent | 2287 | 99.3 |
| Present | 15 | 0.4 |
| Regression (missing = 848; 20%) | ||
| Absent | 2175 | 64 |
| Present | 1226 | 36 |
| Hospital | ||
| 1 | 130 | 3.1 |
| 2 | 698 | 16.4 |
| 3 | 984 | 23.2 |
| 4 | 1210 | 28.5 |
| 5 | 505 | 11.9 |
| 6 | 80 | 1.9 |
| 7 | 284 | 6.7 |
| 8 | 247 | 5.8 |
| 9 | 109 | 2.6 |
Hospital: 1. Hospital Universitario de Salamanca (Salamanca, Spain); 2. Instituto Valenciano de Oncología (Valencia, Spain); 3. Hospital Clìnic (Barcelona, Spain); 4. Hospital de Turin (Turin, Italy); 5. Hospital German Trials i Pujol (Badalona, Spain); 6. Hospital de Coimbra (Coimbra, Portugal); 7. Hospital Universitario A Coruña (A Coruña, Spain); 8. Hospital Virgen Macarena (Seville, Spain); 9. Hospital La Fe (Valencia, Spain).
Abbreviations: ALM, acral lentiginous melanoma; LMM, lentigo maligna melanoma; NM, nodular melanoma; SSM, superficial spreading melanoma.