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Comparison of phospho‐Akt and ‐p53 levels 24 h after treating cultured C26 tumor cells. Reduced phospho‐Akt(Ser473) kinase positive cell populations after mEHT and mEHT + Dox treatments (A). Significantly elevated post‐treatment phospho‐p53(Ser15) levels showing the same highest values after Dox and the combined treatments (B). Increased cytoplasmic to nuclear relocalization of phospho‐p53(Ser15) indicate p53 activation (C). Scale bar: 100 µmol/L. ***P < 0.001
