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. 2019 Aug 2;10(8):576. doi: 10.1038/s41419-019-1814-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a The levels of glutamine, glutamate, and α-KG were examined in circHECTD1-silenced BGC823 cells. b The levels of glutamine, glutamate, and α-KG were examined in circHECTD1-overexpressing SGC7901 cells. c Western blotting was performed to detect the expression levels of ASCT2 and GLS1 in circHECTD1-silenced BGC823 cells. d Western blotting was performed to detect the expression levels of ASCT2 and GLS1 in circHECTD1-overexpressing SGC7901 cells. The data are shown as the mean ± SEM, n = 3. **P < 0.01, ***P < 0.001 vs. NC