FIG 8.
MEF2C knockout reduces ESE targets ETS1 and BCL2 expression. (A) MEF2C, IRF4, EBNA2, SPI1, and H3K27ac ChIP-seq tracks at ETS1 ESE. (B) MEF2C, IRF4, EBNA2, SPI1, and H3K27ac ChIP-seq tracks at BCL2 ESE. (C) Expression level of ETS1 and BCL2 followed by MEF2C knockout in LCLs by qRT-PCR. Levels of control sgRNA treated cells were set to 1. **, P < 0.01; *, P < 0.05.