FIG 3.

Evolution rates do not vary by primary or spillover host or in experimental versus natural FIV infection. Shown are log₁₀ intra-individual evolution rates in primary hosts versus spillover hosts for SIV and FIV (A, B) and in experimental settings relative to natural settings for FIV in domestic cats (C). Sample sizes for primary hosts: FIV, n = 93, and SIV, n = 25. Numbers of spillover host infections: FIV, n = 3, and SIV, n = 46. Sample sizes for experimentally induced FIV infections versus naturally acquired FIV infections: n = 6 versus n = 90. Boxes represent the interquartile ranges of the data, and bars represent the median values. T bars represent the main bodies of data, and open circles represent outlying data points.