TABLE 1.
Mouse strain | % positive swabsb | Peak titerc | Total no. of shedding daysd | No. of days of shedding/mousee | Reactivation rate (%)f | Final day of sheddingg |
---|---|---|---|---|---|---|
B6 | 14 | 3.85 + 0.32 | 10 | 1.9 + 0.14 | 40 | 5 |
B6-CD28KO | 33 | 4.79 + 0.34 | 32 | 3.7 + 0.3 | 65 | 12 |
BALB/c | 11 | 3.65 + 0.38 | 8 | 1.6 + 0.11 | 35 | 6 |
C-CD28KO | 28 | 4.25 + 0.42 | 28 | 3.3 + 0.18 | 55 | 12 |
Data are for 20 mice of each strain.
The percentage of virus-positive eye swabs (140 to 286 eye swab specimens per group) over the 12-day period following UV-B irradiation (P < 0.05 for CD28KO mice).
Peak viral titer, which occurred on day 3 postreactivation, expressed as the number of log10 PFU (P < 0.02 for CD28KO mice).
Total number of days that the mice were swab positive (P < 0.01 for CD28KO mice).
The number of days that a positive mouse shed virus (P < 0.05 for CD28KO mice).
The percentage of mice in which virus was reactivated (P < 0.02 for CD28KO mice).
The last day that a mouse was positive for a particular group.