FIG 3.
Proteins involved in the innate antiviral immune response remain unchanged during BKPyV infection. (A) Up- or downregulation of a minority of proteins with innate antiviral function (UniProt keywords, innate immunity and antiviral). (B) Example protein profiles from the data in panel A. (C) Validation of temporal profiles shown in panel B by Western blotting. RPTE cells were mock infected or infected with BKPyV at an MOI of 3 or stimulated with IFN-α2A (104 U/ml) and analyzed by Western blotting for the proteins shown.