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. 2019 Apr 1;123(2):e303–e311. doi: 10.1016/j.bja.2019.02.021

Table 2.

Results of amplitude of low-frequency fluctuations (ALFF) analysis. Results reported for whole brain ALFF analysis with age and gender as covariates. Amy, amygdala; cLBP, chronic low back pain; dACC, dorsal anterior cingulate cortex; dlPFC, dorsolateral prefrontal cortex; HC, healthy control; Hip, hippocampal gyrus; L, left; MNI, Montreal Neurological Institute; mPFC, medial prefrontal cortex; PCC, posterior cingulate cortex; PCL, paracentral lobule; pHip, parahippocampal gyrus; PoG, postcentral gyrus; PrG, precentral gyrus; R, right; rACC, rostral anterior cingulate cortex; SMA, supplementary motor area; TPJ, temporoparietal junction.

Contrast Regions Peak MNI
Peak z-value Voxels
x y z
cLBP>HC dACC_L −6 36 27 3.97 1812
PoG/PrG_L −42 −6 35 3.90
PoG/PrG_R (upper) 31 −6 52 3.73
SMA/PCL 2 −9 70 3.34
PoG/PrG_R (lower) 57 6 21 3.92 238
rACC 0 42 −3 3.56 221
High pain>low pain Insula_R 42 21 −9 5.11 599
Hip/pHip/Amy_R 27 −6 −36 4.71
Insula_L −36 10 −14 4.33 54
Hip/pHip_L −27 −3 −27 3.97 36
Thalamus_L −6 −12 15 3.34 43
Low pain>high pain TPJ_L −39 −60 30 6.74 41
mPFC/rACC 12 51 30 6.14 5366
dlPFC_L −36 33 27 5.02
dlPFC_R 27 42 27 5.18
Precuneus/PCC −12 −57 60 4.59
TPJ_R 54 −33 48 3.87