Table 2. Univariate and multivariable analysis of demographics, atopic history and investigation parameters with peanut allergy.
Variable | Unadjusted OR (95% CI)* | p value | Adjusted OR (95% CI)† | p value | |
---|---|---|---|---|---|
Demographics | |||||
Male sex | 0.70 (0.39–1.25) | 0.2276 | 0.68 (0.38–1.23) | 0.1995 | |
Age (yr) | 1.57 (0.89–2.78) | 0.1219 | 1.18 (0.64–2.18) | 0.5978 | |
Race, Chinese | 1.12 (0.62–2.03) | 0.7088 | 1.03 (0.56–1.88) | 0.9355 | |
History of atopy | |||||
Rhinitis‡ | 2.52 (1.42–4.47) | 0.0016 | 2.39 (1.30–4.38) | 0.0050 | |
Atopic dermatitis‡ | 0.82 (0.41–1.63) | 0.5745 | 0.80 (0.40–1.62) | 0.5405 | |
Asthma§ | 1.31 (0.61–2.81) | 0.4817 | 0.90 (0.40–2.02) | 0.7915 | |
Drug allergy‡ | 0.70 (0.23–2.16) | 0.5340 | 0.45 (0.14–1.46) | 0.1819 | |
Urticaria/angioedema‡ | 0.61 (0.27–1.36) | 0.2228 | 0.67 (0.29–1.53) | 0.3450 | |
Tree nut allergies∥ | 1.38 (0.73–2.60) | 0.3235 | 1.33 (0.70–2.54) | 0.3779 | |
Other food allergies∥ | 1.57 (0.89–2.76) | 0.1184 | 1.57 (0.87–2.84) | 0.1324 | |
Investigation results | |||||
SPT wheal size (mm)¶ | 4.68 (2.32–9.41) | <0.0001 | 1.32 (1.20–1.45) | <0.0001 | |
IgE to peanut (kU/L)¶ | 1.96 (0.63–6.11) | 0.2438 | 1.09 (1.02–1.17) | 0.0144 |
OR, odds ratio; CI, confidence interval; SPT, skin prick test; IgE, immunoglobulin E.
*Odds ratio using univariate logistic regression analysis. †Odds ratio using multivariable logistic regression analysis; adjusted for age and rhinitis. ‡Parental report of patient's history of rhinitis, atopic dermatitis, drug allergy and urticaria/angioedema. §Physician diagnosed asthma. ∥Clinical diagnosis of tree nut/food allergy based on clinical history and positive SPT/IgE. ¶Odds ratio is reported for the risk of SPT ≥3 mm, and serum IgE ≥0.35 kU/L.