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. 2019 Jul 8;9(3):e21. doi: 10.5415/apallergy.2019.9.e21

Table 3. Diagnostic performance for skin prick test and IgE to peanut, ROC analysis.

Test Cutoff point Unadjusted OR (95% CI) p value Sensitivity (%) Specificity (%) PPV (%) NPV (%) AUC
SPT (mm) 3 4.68 (2.32–9.41) <0.0001 91.5 30.5 85.7 43.9 64.8
4 7.30 (3.92–13.6) <0.0001 87 52.5 89.3 47 68.1
5 7.78 (4.22–14.4) <0.0001 81.4 64.4 91.3 43.2 67.2
6 7.75 (4.12–14.6) <0.0001 74.7 72.9 92.6 38.7 65.7
7 9.10 (4.55–18.2) <0.0001 68.4 81.4 94.4 36.1 65.2
8 9.75 (4.52–21.0) <0.0001 61.7 86.4 95.4 33.1 64.3
9 9.91 (4.23–23.2) <0.0001 54.7 89.8 96.1 30.3 63.2
10 7.64 (3.06–19.0) <0.0001 43.5 91.5 95.9 26.2 61.1
Peanut IgE (kU/L) 0.35 1.96 (0.63–6.11) 0.2438 91 15.4 89.7 17.4 53.5
2 3.50 (1.54–7.97) 0.0028 75.2 53.9 92.9 21.2 57.1
5 3.07 (1.30–7.26) 0.0106 58.6 69.2 93.9 17.1 55.5
6 7.41 (2.97–18.5) <0.0001 42.8 91.5 95.8 26 60.9
7 6.97 (2.80–17.4) <0.0001 41.3 91.5 95.7 25.5 60.6
8 7.79 (2.88–21.1) <0.0001 38.7 93.2 96.3 25 60.6
9 6.53 (2.41–17.7) 0.0002 34.6 93.2 95.9 23.8 59.8
10 3.75 (1.31–10.8) 0.0138 42.9 84.6 95.7 15.5 55.6
20 6.07 (1.12–32.9) 0.0364 26.2 96.2 98.2 13.9 56.1
30 12.6 (0.73–218) 0.0819 19.1 100 100 13.3 56.6
40 9.30 (0.53–164) 0.1275 14.8 100 100 12.7 56.3
50 7.29 (0.41–130) 0.1770 11.9 100 100 12.3 56.2

IgE, immunoglobulin E; ROC, receiver operating characteristic; OR, odds ratio; CI, confidence interval; SPT, skin prick test; PPV, positive predictive value; NPV, negative predictive value; AUC, area under the receiver operator characteristic curve.