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. 2019 Jul 5;18(3):1745–1751. doi: 10.3892/etm.2019.7736

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Copyright: © Che et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Colonic histopathological micrographs and p53 expression levels. Mice were randomly divided into 5 groups (n=12); control group, model group (DSS group) and low, medium and high dose (25, 50 and 100 mg/kg/day respectively) taraxasterol groups. (A) Colonic tissues from each group were stained with H&E (magnification, ×100). The red arrows indicate granulation tissue hyperplasia and glandular enlargement. (B) p53 expression levels (brown staining) were measured by immunohistochemistry assay (magnification, ×100). p53, tumor protein p53; DSS, dextran sodium sulphate; H&E, hematoxylin and eosin.