Figure 2.

Identification of miRNAs involved in 5‐fluorouracil (5‐FU) resistance in colon cancer cells. A, The heatmap of miRNA expression profiles between the 5‐FU treated and non‐treated cells. miR‐31 (arrow) was more frequently overexpressed in 5‐FU resistant cells than 5‐FU non‐treatment cells. B, Expression levels of miR‐31 in parent and 5‐FU‐resistant cells. Right panel: DLD‐1 and DLD/F cells. Left panel: mDLDc, mDLD/F1 and mDLD/F2 cells. The relative expression levels were calculated using the ΔΔCt method, with RNU6B used as a control