Table 4.
Radiosensitization activity of Fadu and Detroit562 cells pretreatment with 4μ8c, 4μ8c+Tunicamycin or control
| Fadu | Detroit562 | |||||
|---|---|---|---|---|---|---|
| Control | 4μ8c | 4μ8c+Tuni | Control | 4μ8c | 4μ8c+Tuni | |
| D0 | 1.60 | 2.00 | 1.40 | 1.45 | 1.68 | 1.20 |
| Dq | 1.97 | 2.62 | 1.71 | 1.76 | 1.98 | 1.56 |
| N | 4.50 | 6.87 | 4.15 | 4.00 | 4.31 | 3.98 |
| SF2 | 0.77 | 0.90 | 0.65 | 0.69 | 0.79 | 0.56 |
| SER | 0.80 | 1.19 | 0.86 | 1.21 | ||
| SD | ||||||
| 2 Gy | 0.02 | 0.04 | 0.03 | 0.04 | 0.06 | 0.03 |
| 4 Gy | 0.04 | 0.07 | 0.05 | 0.02 | 0.01 | 0.02 |
| 6 Gy | 0.02 | 0.05 | 0.01 | 0.01 | 0.03 | 0.02 |
Abbreviations: D0, mean lethal dose; Dq, quasi‐threshold dose; N, extrapolation number, derived directly from the fitting equation; SER, sensitization enhancement ratio; SF2, survival fraction (2 Gy).