Figure 2.

High expression of microRNA (miR)‐30c is related to increased glycolysis in tumor‐associated macrophages (TAMs). A, Hierarchical clustering analysis of glycolysis‐related metabolites that differentially existed between miR‐30c^Low and miR‐30c^High gastric cancer (GC) TAMs (n = 10, each group). B‐D, Determination and comparison of fructose 6 phosphate (B), pyruvate (C), and lactate (D) concentration between miR‐30c^Low and miR‐30c^High groups in GC TAMs. E,F, Transcription of PKM (E) and PFK (F) genes were determined by real‐time PCR in miR‐30c^Low and miR‐30c^High groups in GC TAMs. All experiments were undertaken in triplicate. Data are presented as mean ± SD. Student's t test