Table II.
Key topological characteristics of the hub genes in the co-expression network.
| Gene name | Degree of connectivity | Betweenness centrality | Closeness centrality | No. of directed edges |
|---|---|---|---|---|
| TLR2 | 11 | 0.18228291 | 0.65384615 | 11 |
| GSTO1 | 11 | 0.25733543 | 0.73913043 | 11 |
| MAPK13 | 10 | 0.07893908 | 0.62962963 | 10 |
| RALA | 8 | 0.03345588 | 0.58620690 | 8 |
| IRAK1 | 8 | 0.02447479 | 0.58620690 | 8 |
| TGFA | 7 | 0.08142507 | 0.62962963 | 7 |
| CCL2 | 7 | 0.01197479 | 0.56666667 | 7 |
| PLD1 | 6 | 0.13480392 | 0.54838710 | 6 |
| GNAI3 | 6 | 0.22058824 | 0.54838710 | 6 |
| GNA15 | 6 | 0.03734244 | 0.58620690 | 6 |
| GSTO2 | 5 | 0.76666667 | 0.85714286 | 5 |
| BCL2L1 | 5 | 0.00000000 | 0.53125000 | 5 |
| CDK4 | 5 | 0.01250000 | 0.45945946 | 5 |
TLR2, Toll-like receptor 2; MAPK13, mitogen-activated protein kinase 13; GSTO1, glutathione S-transferase omega 1; GSTO2, glutathione S-transferase o 2; BCL2L1, BCL2 like 1; RALA, RAS like proto-oncogene A; TGFA, transforming growth factor α; CDK4, cyclin dependent kinase 4; PLD1, phospholipase D1; IRAK1, interleukin 1 receptor associated kinase 1; CCL2, C-C motif chemokine ligand 2; GNA15, G protein subunit α 15; GNAI3, G protein subunit α I3.