Figure 4.
Knockdown of H19 promotes the apoptosis of thyroid cancer cells. Cell apoptosis was assessed using flow cytometry following Annexin V-FITC/PI staining. (A) Apoptosis of FTC-133 cells was markedly increased following transfection with H19 siRNA compared with that in the NC group. The differences between the control group and the NC group were not statistically significant. (B) Quantitative analysis of the apoptosis of FTC-133 cells. (C) Apoptosis of TPC-1 cells was markedly increased following transfection of H19 siRNA compared with that in the NC group. The differences between the control group and the NC group were not statistically significant. (D) Quantitative analysis of the apoptosis of TPC-1 cells. **P<0.01. Groups: NC, cells transfected with NC siRNA; siRNA, cells transfected with H19 siRNA. NC, negative control; siRNA, small silencing RNA; FITC, fluorescein isothiocyanate; PI, propidium iodide.