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. 2019 Jul 18;18(3):3170–3176. doi: 10.3892/ol.2019.10636

Figure 2.

Figure 2.

miR-490-3p was lowly expressed in ESCC tissue. (A) miR-490-3p was lowly expressed in ESCC tissues, particularly in advanced esophageal tissues. (B) miR-490-3p was lowly expressed in ESCC tissues, particularly in tissues with tumors >3 cm. (C) miR-490-3p was lowly expressed in ESCC cell lines. Effects of miR-490-3p overexpression and depletion in (D) TE1 and (E) ECA109 cells on miR-490-3p expression level. (F) Gene Set Enrichment Analysis demonstrated that miR-490-3p essentially regulated cell apoptosis. **P<0.01, ***P<0.001. ESCC, esophageal squamous cell carcinoma; miR, microRNA; NC, negative control; KEGG, Kyoto Encyclopedia of Genes and Genomes.