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. 2019 Jul 18;18(3):3170–3176. doi: 10.3892/ol.2019.10636

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Copyright: © Zabihula et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — miR-490-3p induced ESCC cell apoptosis and inhibited ESCC cell proliferation. (A) miR-490-3p overexpression and depletion in TE1 and ECA109 cell lines significantly inhibited and promoted cell proliferation, respectively. Plate cloning experiments using (B) TE1 and (C) ECA109 cells. (D) Flow cytometry analysis of cell apoptosis demonstrated that miR-490-3p overexpression induced ESCC cell apoptosis. (E) The quantification of flow cytometry analysis demonstrated that miR-490-3p overexpression induced ESCC cell apoptosis. **P<0.01. ESCC, esophageal squamous cell carcinoma; OD, optical density; miR, microRNA; NC, negative control.