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. 2019 Jul 18;18(3):3170–3176. doi: 10.3892/ol.2019.10636

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Copyright: © Zabihula et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — MAPK1 overexpression reversed miR-490-3p-induced apoptosis on TE1 cells. (A) MAPK1 relative mRNA level in different groups. (B) Following miR-490-3p overexpression, cell proliferation was significantly reduced. MAPK1 overexpression enhanced cell proliferation. (C) Following miR-490-3p overexpression, cell apoptosis was increased. MAPK1 overexpression significantly reduced cells apoptosis. **P<0.01, ***P<0.001. MAPK1, mitogen-activated protein kinase 1; miR, microRNA; NC, negative control; OD, optical density.