Figure 4.

LINC-PINT is a likely upstream inhibitor of BANCR in melanoma cells. (A) Overexpression of LINC-PINT and BANCR in A375-P and A375-MA2 melanoma cells was achieved 24 h following transfection. (B) LINC-PINT overexpression resulted in BANCR downregulation in both cell lines. (C) BANCR overexpression did not significantly affect LINC-PINT expression. The numbers above each bar indicate the mean value of three replicates. *P<0.05, as indicated. LINC-PINT, long intergenic non-protein coding RNA p53 induced transcript; BANCR, BRAF-activated non-protein coding RNA; C, control (untransfected cells); NC, negative control (cells transfected with empty vectors).