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CTAB enhanced DOX sensitivity on MCF-7/MDR cells. (A) Effect of DOX and DOX combined with CTAB on cell viability of MCF-7/MDR cells for 48 h. Mean values ± SD, *P < 0.05, MCF-7/MDR cells treated with different concentration of DOX for 48 h vs. MCF-7 cells treated with different concentration of DOX combined with CTAB for 48 h. (B) AMPK, p-AMPK, HIF-1α, and P-gp protein expression caused by CTAB treatment.
