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Effects of hyperglycemia on plasma insulin concentrations in lean (n = 6) and obese (n = 6) individuals during a hyperglycemic (10 mmol/L) clamp when plasma acetate concentrations were kept at basal with an acetate infusion of 0.7 μmol/Kg-min and during a high-dose (14 μmol/Kg-min) acetate infusion increasing plasma acetate concentrations ∼5-fold.
