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. 2019 Jun 27;18(3):2340–2347. doi: 10.3892/ol.2019.10534

Figure 2.

Figure 2.

JQ1 decreases VDAC1 expression in a dose- and time-dependent manner. (A) Western blot and (B) RT-qPCR analysis of VDAC1 expression in MCF-7 and T47D cells treated with JQ1 (0.5 and 1 µM) or untreated (0 µM; equal amount of DMSO added) for 24 h (n=3). (C) Western blot and (D) RT-qPCR analysis of VDAC1 expression in MCF-7 and T47D cells treated with JQ1 (0.5 µM) for 24 and 48 h or untreated (0 µM) for 48 h (n=3). *P<0.05, **P<0.01 and ***P<0.001. VDAC1, voltage-dependent anion-selective channel 1; RT-qPCR, reverse transcription-quantitative polymerase chain reaction.