Figure 4.

Western blot analysis of protein expression levels. (A) Expression levels of MMP14, MMP15, MMP16, MMP24 and TIMP2 in the CT and NC groups. (B) Following treatment with cryptotanshinone, the expression level of MMP14 was significantly downregulated, while no significant differences were identified for the other proteins. GAPDH was used as control. Data are presented as the mean ± standard deviation. *P<0.05 vs. NC group. MMP, matrix metalloproteinase; TIMP2, tissue inhibitor of metalloproteinases 2; CT, cryptotanshinone-treated; NC, negative control.