. 2019 Jul 26;13:763. doi: 10.3389/fnins.2019.00763

TABLE 1.

Demographic and neuropsychological assessment data of the participants.

Variables	Female				Male
	Dis (n = 8)	High (n = 16)	HC (n = 31)	P	Dis (n = 15)	High (n = 9)	HC (n = 18)	P
Demographic data
Age (years)	61.13 ± 7.22	57.88 ± 8.65	56.48 ± 12.21	0.549^a	51.20 ± 15.67	57.89 ± 15.99	63.39 ± 7.58	0.035^*a
Education (years)	10.50 ± 2.27	9.44 ± 2.80	10.42 ± 3.43	0.563^a	13.00 ± 3.21	9.22 ± 4.09	11.06 ± 2.98	0.031^*a
BMI (kg/m²)	25.02 ± 2.32	24.68 ± 2.26	23.60 ± 2.57	0.203^a	24.21 ± 2.50	25.92 ± 4.05	23.94 ± 2.88	0.270^a
Blood biochemical indices
FPG (mmol/L)	5.30 ± 0.75	5.05 ± 1.16	4.56 ± 0.93	0.096^a	4.63 ± 0.96	4.34 ± 0.84	5.34 ± 1.38	0.070^a
CHO (mmol/L)	5.54 ± 0.71	5.28 ± 1.05	4.81 ± 0.77	0.053^a	4.60 ± 0.92	4.89 ± 0.61	4.54 ± 0.89	0.596^a
TRI (mmol/L)	1.59 ± 1.11	1.70 ± 0.80	1.44 ± 1.07	0.696^a	1.58 ± 1.38	1.44 ± 0.95	1.18 ± 0.65	0.538^a
HDL-C(mmol/L)	1.35 ± 0.26	1.47 ± 0.18	1.49 ± 0.32	0.424^b	1.33 ± 0.35	1.13 ± 0.23	1.28 ± 0.29	0.273^a
LDL-C(mmol/L)	3.63 ± 0.80	3.14 ± 0.81	2.69 ± 0.62	0.003^⁣a	2.65 ± 0.67	3.06 ± 0.81	2.73 ± 0.73	0.393^a
Scr (μmol/L)	66.61 ± 11.56	52.34 ± 7.67	51.60 ± 10.73	0.002^⁣a	75.07 ± 9.44	72.02 ± 11.17	70.76 ± 10.08	0.473^a
eGFR (ml/min/1.73 m²)	97.00 ± 17.00	131.38 ± 23.28	137.13 ± 23.03	0.001^⁣a	109.67 ± 20.92	113.78 ± 25.97	113.17 ± 23.03	0.880
Neuropsychological assessment
MMSE	26.88 ± 2.42	27.88 ± 1.89	27.87 ± 1.78	0.401^a	28.67 ± 1.35	27.22 ± 1.72	27.78 ± 1.44	0.061^a
MoCA	23.75 ± 3.77	24.94 ± 3.19	25.35 ± 2.69	0.408^a	25.93 ± 2.96	26.11 ± 3.41	25.17 ± 2.46	0.642^a
Vocabulary learning (n)	14.63 ± 3.96	16.50 ± 5.62	17.87 ± 5.74	0.309^a	17.73 ± 6.43	13.78 ± 10.11	15.72 ± 4.57	0.373^b
Delayed recall (n)	3.88 ± 3.00	4.69 ± 2.55	5.23 ± 2.57	0.413^a	5.40 ± 3.20	4.44 ± 3.54	5.22 ± 2.00	0.712^a
NCT(s)	84.50 ± 88.13	55.69 ± 23.39	64.83 ± 39.05	0.355^b	42.80 ± 17.29	73.78 ± 27.11	73.44 ± 49.51	0.042^*a
DST(n)	32.50 ± 13.47	37.25 ± 13.10	43.29 ± 21.66	0.277^a	46.60 ± 14.43	38.56 ± 23.17	36.11 ± 17.50	0.242^a
LTT(s)	57.25 ± 16.28	45.75 ± 21.56	54.26 ± 40.87	0.645^a	43.20 ± 24.42	48.00 ± 11.34	48.28 ± 21.88	0.767^a
SDT(s)	55.13 ± 12.17	46.06 ± 14.15	51.06 ± 20.06	0.458^a	38.47 ± 10.59	49.78 ± 17.25	51.33 ± 23.82	0.133^a
Word fluency (n)	3.50 ± 2.51	4.44 ± 2.76	3.74 ± 2.41	0.596^a	4.93 ± 1.98	2.78 ± 2.17	5.61 ± 2.99	0.029^*a
StroopI(s)	18.88 ± 7.79	18.06 ± 7.16	19.45 ± 7.79	0.839^a	23.20 ± 9.88	23.67 ± 8.80	19.61 ± 7.53	0.388^a
StroopII(s)	24.63 ± 7.37	26.00 ± 6.46	24.42 ± 8.25	0.764^a	29.87 ± 8.63	29.11 ± 9.44	27.56 ± 9.16	0.758^a
StroopIII(s)	30.75 ± 11.02	32.25 ± 7.75	32.16 ± 9.46	0.920^a	38.20 ± 8.93	38.00 ± 10.20	36.00 ± 14.41	0.847

Mean ± standard deviation; s, second; n, number; MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment; NCT, number connection test; DST, digit symbol test; LTT, line tracing test; SDT, serial dotting test; FPG, Fasting plasma glucose; CHO, cholesterol; TRI, triglyceride; HDL-C, High-density lipoprotein cholesterol; LDL-C, Low-density lipoprotein cholesterol; Scr, serum creatinine; eGFR, estimated glomerular filtration rate; ^*P < 0.05, ^∗∗P < 0.01; ^a LSD(L); ^bTamhane’s T2(M).