Table II.
Comparison of the seven serum indices in normal controls and patients with cervical cancer.
| Normal | SCC | Normal vs. SCC | AC | Normal vs. AC | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Serum index | n | Mean ± SD | n | Mean ± SD | OR (95% CI) | P-value | n | Mean ± SD | OR (95% CI) | P-value |
| CA-125 | 246 | 16.530±8.573 | 137 | 29.923±73.543 | 1.028 (1.011–1.044) | 0.035 | 16 | 24.644±29.386 | 1.037 (1.007–1.068) | 0.288 |
| CA-199 | 220 | 10.614±7.762 | 114 | 16.603±24.190 | 1.026 (1.008–1.044) | 0.011a | 12 | 10.497±6.714 | 0.998 (0.925–1.077) | 0.959 |
| AFP | 387 | 3.487±2.475 | 129 | 3.008±1.764 | 0.897 (0.806–0.998) | 0.043a | 15 | 3.053±2.036 | 0.909 (0.687–1.203) | 0.503 |
| CEA | 388 | 2.426±2.807 | 134 | 10.178±67.004 | 1.096 (1.039–1.157) | 0.183 | 16 | 3.619±3.654 | 1.073 (0.976–1.181) | 0.216 |
| ALP | 237 | 53.236±16.262 | 218 | 72.168±24.482 | 1.052 (1.039–1.065) | 9.58×10−20c | 21 | 65.990±23.815 | 1.032 (1.011–1.054) | 0.001b |
| Cholesterol | 388 | 4.645±0.823 | 160 | 4.876±1.093 | 1.316 (1.076–1.610) | 0.017a | 18 | 5.258±0.928 | 2.295 (1.332–3.956) | 0.002b |
| TG | 388 | 1.105±0.526 | 158 | 1.679±1.074 | 3.226 (2.325–4.477) | 1.14×10−9c | 18 | 1.708±0.940 | 2.774 (1.594–4.827) | 0.015a |
a
P<0.05
b
P<0.01
c
P<0.001. SCC, squamous cell carcinoma; AC, cervical adenocarcinoma; CA, sugar chain antigen; AFP, α fetoprotein; CEA, carcino-embryonic antigen; ALP, alkaline phosphatase; TG, triglyceride; SD, standard deviation; OR, odds ratio; CI, confidence interval.