Table IV.
Comparison of the seven serum indices by age variation in normal controls, patients with SCC and patients with AC.
| A, Normal | ||||||
|---|---|---|---|---|---|---|
| Age | ||||||
| <40 years | 40–50 years | <40 years vs. 40–50 years | ||||
| Serum index | n | Mean ± SD | n | Mean ± SD | OR (95% CI) | P-value |
| CA-125 | 163 | 17.189±8.718 | 56 | 16.850±8.691 | 0.995 (0.960–1.032) | 0.802 |
| CA-199 | 150 | 10.528±7.794 | 49 | 9.249±6.476 | 0.975 (0.930–1.023) | 0.301 |
| AFP | 257 | 3.240±2.151 | 92 | 4.129±3.180 | 1.136 (1.039–1.243) | 0.014a |
| CEA | 257 | 2.355±3.005 | 93 | 2.605±2.529 | 1.028 (0.952–1.109) | 0.474 |
| ALP | 150 | 51.600±15.236 | 60 | 50.850±12.791 | 0.996 (0.976–1.018) | 0.737 |
| Cholesterol | 257 | 4.480±0.807 | 94 | 4.876±0.776 | 1.852 (1.360–2.523) | 4.84×10−5c |
| TG | 257 | 1.015±0.466 | 94 | 1.252±0.650 | 2.214 (1.400–3.502) | 0.002b |
| B, SCC | ||||||
| Age | ||||||
| <40 years | 40–50 years | <40 years vs. 40–50 years | ||||
| Serum index | n | Mean ± SD | n | Mean ± SD | OR (95% CI) | P-value |
| CA-125 | 14 | 19.107±8.060 | 54 | 21.213±21.154 | 1.007 (0.971–1.044) | 0.717 |
| CA-199 | 11 | 14.271±11.415 | 46 | 19.029±28.154 | 1.009 (0.976–1.043) | 0.587 |
| AFP | 12 | 4.603±3.513 | 53 | 2.722±1.187 | 0.660 (0.473–0.920) | 0.093 |
| CEA | 12 | 4.047±8.508 | 54 | 3.991±6.923 | 0.999 (0.915–1.090) | 0.981 |
| ALP | 28 | 56.843±13.926 | 97 | 64.723±18.471 | 1.028 (1.001–1.056) | 0.039a |
| Cholesterol | 18 | 4.508±0.691 | 67 | 4.563±1.015 | 1.065 (0.610–1.858) | 0.828 |
| TG | 18 | 1.273±0.678 | 67 | 1.395±0.713 | 1.313 (0.579–2.974) | 0.518 |
| C, AC | ||||||
| Age | ||||||
| <40 years | 40–50 years | <40 years vs. 40–50 years | ||||
| Serum index | n | Mean ± SD | n | Mean ± SD | OR (95% CI) | P-value |
| CA-125 | 4 | 17.625±10.356 | 4 | 37.000±35.849 | 1.040 (0.962–1.124) | 0.365 |
| CA-199 | 4 | 14.740±8.105 | 3 | 12.550±6.856 | 0.950 (0.753–1.198) | 0.722 |
| AFP | 4 | 2.115±1.051 | 3 | 4.023±1.932 | 4.236 (0.351–51.105) | 0.149 |
| CEA | 4 | 5.020±6.482 | 4 | 2.880±2.929 | 0.890 (0.624–1.269) | 0.569 |
| ALP | 5 | 58.180±7.811 | 6 | 66.167±41.732 | 1.011 (0.965–1.058) | 0.686 |
| Cholesterol | 4 | 4.878±0.970 | 5 | 4.850±0.768 | 0.953 (0.168–5.395) | 0.963 |
| TG | 4 | 1.360±0.920 | 5 | 1.604±0.544 | 1.808 (0.218–15.012) | 0.633 |
a
P<0.05
b
P<0.01
c
P<0.001. SCC, squamous cell carcinoma; AC, cervical adenocarcinoma; CA, sugar chain antigen; AFP, α fetoprotein; CEA, carcino-embryonic antigen; ALP, alkaline phosphatase; TG, triglyceride; SD, standard deviation; OR, odds ratio; CI, confidence interval.