Table I.

Inhibition rates of metformin with indicated concentrations and incubation times in SKOV3 and SKOV3/DDP cells.

Concentration (mmol/l)	Time (h)	SKOV3 (%±SD)	SKOV3/DDP (%±SD)	t-statistic	P-value
2.5	24	10.80±1.78	13.14±2.94	0.290	0.779
	48	18.41±1.94	16.84±1.90	−0.470	0.651
	72	22.20±1.19	24.89±2.22	3.275	0.061
5	24	16.25±1.60	18.82±1.92	3.301	0.050
	48	23.01±2.76	22.46±2.56	−0.330	0.750
	72	27.62±1.62	31.84±2.25	3.398	0.009
10	24	20.30±1.69	27.97±1.82	6.904	<0.001
	48	27.95±2.69	34.35±2.39	3.984	0.004
	72	33.30±3.56	38.04±2.90	2.309	0.041

N=3/group. DDP, cisplatin; SD, standard deviation.