Table II.

HUWE1 expression in cancer types.

Cancer type	P-value	Fold-change	Sample size, n	(Refs.)
Brain
Glioblastoma	2.70×10−5	−2.428	84	(30)
Glioblastoma	8.42×10−5	−3.928	54	(31)
Anaplastic oligoastrocytoma	3.00×10−3	−2.916	54	(31)
Anaplastic oligodendroglioma	2.80×10−2	−2.667	54	(31)
Glioblastoma	3.20×10−2	−3.046	38	(46)
Oligoastrocytoma	4.00×10−2	−2.045	38	(46)
Glioblastoma	2.92×10−10	−2.045	180	(32)
Breast
Mixed lobular and ductal breast carcinoma	1.70×10−5	2.693	68	(60)
Invasive breast carcinoma	3.09×10−19	−5.100	59	(33)
Leukemia
Chronic lymphocytic leukemia	2.00×10−3	2.562	111	(47)
Lung
Squamous cell lung carcinoma	9.00×10−3	3.019	203	(48)
Small cell lung carcinoma	2.80×10−2	2.137	73	(59)
Lymphoma
Diffuse large B-cell lymphoma	1.00×10−2	−3.503	27	(50)
Marginal zone B-cell lymphoma	8.00×10−3	−3.615	27	(50)
Other
Testicular seminoma	2.00×10−3	11.159	30	(51)
Prostate
Prostate carcinoma	5.00×10−3	6.016	30	(52)
Prostate carcinoma	3.40×10−2	−2.207	19	(53)
Sarcoma
Round cell liposarcoma	6.00×10−3	−3.047	54	(54)

HUWE1, E3 ubiquitin-protein ligase; TCGA, The Cancer Genome Atlas.