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. 2019 Apr 24;123(1):17–26. doi: 10.1016/j.bja.2019.03.022

Table 2.

Chronotropic incompetence and 1 yr mortality. The independent variable was chronotropic incompetence (defined as chronotropic index [CI] <0.6). The dependent variable was mortality within the 1 yr follow-up period. Results of two separate analyses are presented: firstly, univariable (unadjusted) logistic regression analysis, and secondly, multivariable logistic regression adjusting for three variables found to be associated with the dependent variable. The following variables were excluded from the final multivariable model: diabetes mellitus, peripheral vascular disease, atrial fibrillation, high-risk surgery, previous stroke or transient ischaemic attack, clinical diagnosis of heart failure, and preoperative renal insufficiency. Results are presented as odds ratios with 95% confidence intervals and associated P-values.

Co-variates Mortality
Odds ratio P-value
Univariable analysis
 Chronotropic incompetence 2.26 (1.13–4.51) 0.02
Multivariable analysis
 Male sex 2.22 (0.98–5.03) 0.06
 History of stroke or transient ischaemic attack 3.00 (0.99–9.03) 0.05
 History of chronic obstructive pulmonary disease 2.61 (1.17–5.86) 0.02
 CI <0.6 1.98 (0.97–4.02) 0.06