. Author manuscript; available in PMC: 2019 Aug 2.

Published in final edited form as: Toxicol Pathol. 2013 Feb 19;41(8):1093–1105. doi: 10.1177/0192623313477256

Table 1.—

Selected alterations in serum biochemical parameters after single-dose treatment with AFB₁.

Time (day)	Dose (μg/kg)	AST (U/L)	ALT (U/L)	ALP (U/L)	CK (U/L)	Amylase (U/L)	Total Protein (g/dl)	Albumin (g/dl)	Glucose (mg/dl)
1	0	128.00 ± 1.41^a	54.50 ± 0.71^a	403.50 ± 0.71^a	829.50 ± 31.82^a	2,261.00 ± 18.38^a	6.30 ± 0.00^a	4.35 ± 0.07^a	219.00 ± 2.83^a
	50	119.50 ± 0.71^a	48.00 ± 2.00^a	413.00 ± 4.24^a	720.00 ± 8.49^b	2,233.50 ± 2.12^a	6.20 ± 0.00^b	4.30 ± 0.00^a	242.00 ± 2.83^b
	250	274.00 ± 7.07^b	174.50 ± 7.78^b	398.00 ± 8.48^a	828.00 ± 2.83^a	1,915.00 ± 21.21^b	5.95 ± 0.07^c	4.25 ± 0.07^a	169.00 ± 2.83^c
	1,000	2,489.50 ± 102.53^c	1,854.50 ± 106.77^c	485.50 ± 3.53^b	1122.50 ± 6.36^c	488.50 ± 10.61^c	5.25 ± 0.07^d	3.90 ± 0.00^a	93.00 ± 1.41^d
3	0	107.00 ± 4.24^a	49.50 ± 3.54^a	339.50 ± 10.60^a	638.50 ± 17.68^a	2,415.00 ± 110.31^a	6.35 ± 0.21^a	4.45 ± 0.07^a	212.50 ± 7.78^a
	50	97.50 ± 2.12^a	48.00 ± 1.41^a	280.00 ± 5.66^b	485.00 ± 9.90^b	2,483.00 ± 21.21^a	6.05 ± 0.21^a,b	4.25 ± 0.07^a	234.00 ± 5.66^a
	250	442.00 ± 1.41^b	355.00 ± 1.41^b	298.50 ± 0.71^b	569.50 ± 6.36^c	2,523.00 ± 29.70^a	5.60 ± 0.00^b	3.80 ± 0.00^b	188.50 ± 0.71^b
	1,000	10,232.00 ± 284.26^c	6,150.50 ± 58.69^c	639.50 ± 6.36^c	414.50 ± 4.95^d	1,002.00 ± 14.14^b	3.75 ± 0.07^c	3.00 ± 0.00^c	60.00 ± 1.41^c
7	0	143.00 ± 1.41^a	65.00 ± 3.00^a	362.50 ± 2.12^a	851.50 ± 2.12^a	2,510.50 ± 23.33	6.10 ± 0.00	4.20 ± 0.00	200.50 ± 0.71
	50	87.50 ± 4.95^b	38.00 ± 2.83^b	251.50 ± 10.61^b	505.50 ± 16.26^b	2,161.00 ± 83.44	5.85 ± 0.21	4.10 ± 0.14	204.50 ± 6.36
	250	81.00 ± 7.07^b	42.50 ± 0.71^b	250.00 ± 11.31^b	383.50 ± 51.62^b	2,384.00 ± 124.45	6.10 ± 0.14	4.20 ± 0.00	213.00 ± 15.56
21	0	98.00 ± 2.83^a	43.50 ± 2.12	245.50 ± 2.12^a	618.50 ± 6.36^a	2,663.00 ± 14.14	6.35 ± 0.07	4.30 ± 0.00	182.00 ± 1.41^a
	50	87.50 ± 6.36^a,b	36.50 ± 2.12	209.00 ± 2.83^b	443.50 ± 57.28^a,b	2,340.50 ± 23.33	6.25 ± 0.07	4.35 ± 0.07	198.00 ± 12.73^a,b
	250	74.00 ± 4.24^b	43.00 ± 4.24	224.50 ± 0.71^c	327.00 ± 32.53^b	2,636.00 ± 141.42	6.35 ± 0.07	4.40 ± 0.00	224.00 ± 9.90^b

Note. ALP, alkaline phosphatase; ALT, alanine transaminase; AST, aspartate transaminase; CK, creatine kinase.

Values are means ± SD for 5 rats. Values that do not share a label (a letter or blank) are significantly different (p < .05).