Skip to main content
. 2019 Aug;60(10):3320–3331. doi: 10.1167/iovs.18-25647

Figure 5.

Figure 5

Treatment with VP1-001 significantly reduces cataract grade and refractive measures in aged WT C57BL/6J mice, but ent-VP1-001 is inactive. (A, top) Cataract grading for aged WT C57BL/6J mice treated with either compound. Vehicle group represents contralateral eyes from both treatment groups. (A, bottom) Age distribution of WT C57BL/6J mice separated by treatment condition. Each point represents an individual mouse lens. The mean is shown by a dotted line, and the error bars represent the standard errors from the means. (B) Comparison of GPC RALS of water-soluble fractions from homogenized lens tissues of VP1-001 or ent-VP1-001–treated and contralateral vehicle-treated eyes.